Home Research Research Areas Bio Sensor

Biosensor and Microfluidics

Dr. Jungtae Kim, Dr. Jaeho Lee, Prof. Dr. Andreas Manz
We are aiming on keeping our lives from toxic and hazardous substances in our surroundings, and focus on the development of Bio/environmental sensors by means of interdisciplinary research, such as combination of microfluidics, material science, electrochemistry, mechanical engineering and so on.
Living organisms are affected by chronic exposure to chemicals even in very low concentration. The environmental samples, e.g. ground water, contains a number of pollutants which cause disruption in eco-system. Effective monitoring of chemicals in environmental samples and determination of the moment of abnormal behavior of living organism require highly sensitive and accurate sensors with simple sample pretreatment.
Our group is conducting research to realize them by integration of different components from various disciplines.

Biosensor, Microfluidics: separation and pre-concentration of target substances

Split flow chip for capillary electrophoresis

Free flow isotachophoresis for target enrichment

Material science/Biology: target selective probes, biomimetic 3-D cell culture

Target selective probes (e. g. MIP approach)

3D liver cell culturing in microfluidic environment

Electrochemistry: highly sensitive detection system

Electrochemiluminescence spectrometer

References

Superheated droplets for protein thermal stability analyses of GFP, BSA and Taq-Polymerase CD Ahrberg, A Manz RSC Adv., 2016,
DOI: 10.1039/C6RA07079E
Palm-sized device for point-of-care Ebola detection C Ahrberg, A Manz, P Neuzil Anal. Chem
DOI: 0.1021/acs.analchem.6b00278
Pyrosequencing on a glass surface AV Almeida, A Manz, P Neuzil Lab Chip 16, 1063-1071
Plant leaves as templates for soft lithography W Wu, RM Guijt, YE Silina, M Koch, A Manz RSC Advances 6, 22469-22475
Handheld Real-Time PCR Device CD Ahrberg, A Manz, P Neuzil Lab Chip 16, 586-592
A Cytochrome P4503A4 Biosensor Based on Generation 4.0 PAMAM Dendrimers for the Detection of Caffeine Michael Müller, Neha Agarwal and Jungtae Kim Biosensors 2016, 6, 44;
DOI:10.3390/bios6030044
Effects of Antimicrobial Air Filters on the Viability and Culturability of Airborne Bacteria Gi Byoung Hwang, Bo Mi Kwon, Seung Jae Lee, Kyoung Mi, Sim, Gwi-Nam Bae, Jae Hee Jung Clean-Soil, Air, Water 2016,44(9999), 1-10
DOI: 10.1002/clen.201300719
Polymerase Chain Reaction in Microfluidic Devices CD Ahrberg, A Manz, BG Chung Lab Chip 16
DOI: 10.1039/C6LC00984K
Selective and vertical microfabrication of lipid tubule arrays on glass substrates sing templateguided gentle hydration MC Park, P Sukumar, SK Kim, JY Kang, A Manz, TS Kim Lab Chip 16, 4732-4741
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